UPDATE 2021:
I've been told that this video has hit Vimeo's upper bandwidth limit and so I've had to find ways to limit the bleed by either making it private or turning off embedding. I'm trying the latter to see if that works. Apologies for the inconvenience everyone.
UPDATE 2012:
Thanks for all your kind words guys! It's quite overwhelming to see this shared and retweeted all over!
All sins typographic in nature have been amended, hopefully. Thanks for bearing with it the whole time. :)
As always, all credit due to the amazing Ira Glass.
Source audio is from this very seminal video by current.tv:
youtube.com/watch?v=BI23U7U2aUY
Made in three days on Illustrator and After Effects, for Day 6 of the #30daysofcreativity.